The Princess Margaret (PM) RNA Medicine Core is a non-profit academic center specializing in mRNA synthesis, ionizable lipid synthesis, and RNA-based drugs (e.g. siRNA, ASOs, and mRNA) encapsulated lipid nanoparticles(LNP) synthesis. We offer cost-effective, high-quality RNA medicine services. Our advanced facilities and expert team collaborate with academic and industry partners to develop and test new RNA-based therapies.

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We support RNA-LNPs preparation for dry run tests (i.e., 2-50 µg), in vitro scale (100-500 µg), and in vivo scale (> 1 mg) of mRNA/siRNA/ASO. Our quality control (QC) processes ensure the integrity, purity, and functionality of RNA samples, as well as the particle size, particle uniformity, and encapsulation efficiency of RNA-LNPs in various preparation scales.
 

Visit our website to learn more about our services, team, and facilities. Whether you’re interested in RNA molecule design, in vitro and in vivo studies, or developing RNA-based therapies, we have the expertise and resources to support your research goals. If you need a service not listed, please inquire!